The Department of Biological Engineering offers a Doctor of Philosophy (PhD) and Doctor of Science (ScD) in Biological Engineering; the program is the same for both degrees. The Biological Engineering doctoral program educates students to use engineering principles in the analysis and manipulation of biological systems, allowing them to solve problems across a spectrum of important applications. The curriculum is inherently interdisciplinary in that it brings together engineering and biology as fundamentally as possible and cuts across the boundaries of the traditional engineering disciplines.
The student selects a research advisor, typically by the start of the spring term in the first year, and begins research before the end of that year. The oral doctoral qualifying examination, which focuses on the student's area of research, is taken prior to December 1 of the third year. A total of approximately five years in residence is needed to complete the doctoral thesis and other degree requirements. Upon successful completion of the program, students are awarded either the PhD or ScD in Biological Engineering.
Students admitted to the Biological Engineering doctoral program typically have a bachelor's or master's degree in science or engineering. Foundational coursework in biochemistry and molecular cell biology is required prior to admission to the graduate program. During their first year, students pursue a unified core curriculum in which engineering approaches are used to analyze biological systems and technologies over a wide range of length and time scales. The subjects in the unified core bring central engineering principles to bear on the operation of biological systems from molecular to cell to tissue/organ/device systems levels. These are then supplemented by graduate-level electives in the biological sciences and engineering to enhance breadth and depth.
Faculty members associated with the program possess a wide range of research interests. Areas in which students may specialize include systems and synthetic biology; biological and physiological transport phenomena; biological imaging and functional measurement; biomolecular engineering; cell and tissue engineering; computational modeling of biological and physiological systems; bioinformatics; design, discovery, and delivery of molecular therapeutics; molecular, cell, and tissue biomechanics; development of in vitro models of the immune system and lymphoid tissue; development of molecular methods for direct measurement of mutations in humans; metabolism of foreign compounds; genetic toxicology; the molecular aspects and dosimetry of interactions between mutagens and carcinogens with nucleic acids and proteins; molecular mechanisms of DNA damage and repair; design and mechanisms of action of chemotherapeutic agents; environmental carcinogenesis and epidemiology; molecular mechanisms of carcinogenesis; cell physiology; extracellular regulation and signal transduction; molecular and pathologic interactions between infectious microbial agents and carcinogens; and new tools for genomics, proteomics, and glycomics.
