Control and inhibition of virus replication

Summary

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets.

You will be involved in a highly novel project which utilises a multidisiplinary approach and cutting-edge methodology - combining molecular virology, genomics, quantitative proteomics, structural biology, imaging, cell biology and structural-based rational drug design. Consequently, you will gain experience across wide range of molecular biology, cell culture and virological techniques.

This is just one example of the sort of project available in my research group. The precise project will be decided upon in consultation.

For further information please see my web sites.

Dr Andrew Tuplin – Faculty of Biological Sciences

Dr Andrew Tuplin – Astbury Centre

Applicants to research degree programmes should normally have at least a first class or an upper second class British Bachelors Honours degree (or equivalent) in an appropriate discipline. The criteria for entry for some research degrees may be higher, for example, several faculties, also require a Masters degree. Applicants are advised to check with the relevant School prior to making an application. Applicants who are uncertain about the requirements for a particular research degree are advised to contact the School or Graduate School prior to making an application.

The minimum English language entry requirement for research postgraduate research study is an IELTS of 6.0 overall with at least 5.5 in each component (reading, writing, listening and speaking) or equivalent. The test must be dated within two years of the start date of the course in order to be valid. Some schools and faculties have a higher requirement.