Optimising functional independence across the life and healthspan using neurostimulation

Summary

Neuroplasticity is integral to recovery and maintenance of functional independence as we age, and even more crucial in individuals with developmental disorders such as Cerebral Palsy and those with injuries to their brain and/or central nervous system (Spinal Cord Injury, Stroke, MS).

Driving and optimising neuroplasticity using task specific practice, and physical activity in combination with neurostimulation is a growing area of research, however we still have many unanswered questions.

In this project the student will have the option to shape their PhD studies to their interest of choice while aligning it with the academic’s broader research network. Our lab facilities include motion capture, surface and high-density surface EMG, TMS, TDCS, and we can also deliver and measure peripheral and spinal stimulation. We have close links to local hospitals, and the Leeds community, with established collaborations across the University.

We are particularly interested in students wishing to focus their attention on using brain and spinal stimulation to drive upper limb recovery after spinal cord injury, stroke, and multiple sclerosis. We would also be interested in how these types of stimulation might be combined with other neuroplasticity inducing techniques. This includes robotics, hypoxic training, motor imagery, and exercise paradigms in addition to conventional physiotherapy.

The lab also has a focus on how we best drive neuroplasticity for maintaining function as we age. We might ask questions such as how physical activity promotes functional independence and prevents falls (see here for an example), or how we combine non-invasive brain function to increase the tolerability of exercise intensity. This work will dovetail with the primary supervisors Reimaging Ageing Network and you would benefit from a pool if interdisciplinary supervisors.

Applicants to research degree programmes should normally have at least a first class or an upper second class British Bachelors Honours degree (or equivalent) in an appropriate discipline. The criteria for entry for some research degrees may be higher, for example, several faculties, also require a Masters degree. Applicants are advised to check with the relevant School prior to making an application. Applicants who are uncertain about the requirements for a particular research degree are advised to contact the School or Graduate School prior to making an application.

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