Computational modelling: Neural Control of Behaviour

Summary

C. elegans are microscopic worms with a hard-wired and completely mapped neural circuit consisting of precisely 302 nerve cells in the adult. Whilst the primitive behaviours of the worm are relatively well characterised, there is still relatively little understanding of the neural control of these behaviours. In this project, you will focus on one or a small subset of specific behaviours.

The aim of the project is to construct computational models of the worm that impose appropriate dynamics on the hard-wired circuit. Rigorous model analysis then generates biologically testable predictions that will lead to iteration cycles of computational modelling and biological experimentation. Specific projects may focus purely on the computational or experimental aspects, or may combine the two.

Applicants to research degree programmes should normally have at least a first class or an upper second class British Bachelors Honours degree (or equivalent) in an appropriate discipline. The criteria for entry for some research degrees may be higher, for example, several faculties, also require a Masters degree. Applicants are advised to check with the relevant School prior to making an application. Applicants who are uncertain about the requirements for a particular research degree are advised to contact the School or Graduate School prior to making an application.

The minimum English language entry requirement for research postgraduate research study is an IELTS of 6.5 overall with at least 6.5 in writing and at 6.0 in reading, listening and speaking) or equivalent. The test must be dated within two years of the start date of the course in order to be valid. Some schools and faculties have a higher requirement.