Computational modelling of the development of spinal cord neural circuit activity

Summary

Understanding changes in the spinal cord sensori-motor apparatus is highly relevant in our understanding of neurodegenerative diseases that affect motor control in humans, and IS essential for well working prostheses with a neural interface. This project focuses on the role of interneuron populations in spinal cord during development. The developmental change in these populations clearly affects behaviour, but the local neural interactions between these populations resulting in behaviour changes are unclear. Chakrabarty lab in the Faculty of Biological Sciences has obtained accurate population level data on these changing interneuron populations, while Marc de Kamps of the School of Computing has developed innovative methods for modelling neural populations. You will model the neural circuits that control motor behaviour at THE population level in order to gain an understanding of the role of different populations of interneurons in different stages of development. Good mathematical and analytical skills are required, as well as programming experience. A background in computational neuroscience is desirable, but not essential.

Applicants to research degree programmes should normally have at least a first class or an upper second class British Bachelors Honours degree (or equivalent) in an appropriate discipline. The criteria for entry for some research degrees may be higher, for example, several faculties, also require a Masters degree. Applicants are advised to check with the relevant School prior to making an application. Applicants who are uncertain about the requirements for a particular research degree are advised to contact the School or Graduate School prior to making an application.

The minimum English language entry requirement for research postgraduate research study is an IELTS of 6.5 overall with at least 6.5 in writing and at 6.0 in reading, listening and speaking) or equivalent. The test must be dated within two years of the start date of the course in order to be valid. Some schools and faculties have a higher requirement.