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    Infectious Disease 'Omics
    Go to London School of Hygiene & Tropical Medicine, University of London
    London School of Hygiene & Tropical Medicine, University of London

    Infectious Disease 'Omics

    London School of Hygiene & Tropical Medicine, University of London

    London School of Hygiene & Tropical Medicine, University of London

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    United Kingdom, Camden

    Key Facts

    Program Level

    Certificate

    Study Type

    Full Time

    Delivery

    On Campus

    Campuses

    Main Site

    Program Language

    English

    Start & Deadlines

    Next Intake Deadlines5-Dec-2023
    Apply to this program

    Go to the official application for the university

    Duration 1 year(s)
    Next Intake 5-Dec-2023

    Infectious Disease 'Omics

    About

    Overview
    Overview - Infectious Disease 'Omics
    Paragraph

    Infectious diseases, such as HIV-AIDS, malaria, pneumonia and tuberculosis, account for 25% of global mortality and more than half of all deaths in children under the age of five years. The genetic epidemiology of these diseases can be complex, especially as they may involve several genomes, including the host, pathogen(s) and a vector. There is also a need to look beyond the genome to consider other ‘omes, such as the transcriptome, in a more systems biology framework.

    High throughput genotyping and sequencing technologies are providing insights into these genomes, metabolomes, transcriptomes and proteomes, thereby revolutionising genetic epidemiological studies and biomedical research. The use of SNP chips in large-scale genome-wide studies of association and genic selection has revolutionized the study of human disease susceptibility. Whole genome studies of pathogens using high throughput sequencing technologies is leading to the ability to track microbial evolution over time and space, as well as identify variants correlated with phenotypes such as anti-microbial resistance. Further, RNAseq methodologies are being used to measure transcript abundance and differential gene expression across isolates.

    To take full advantage of new ‘omic technologies requires the ability to analyse large amounts of data using methods from bioinformatics, population genetics and statistics – the focus of this course. Specifically, this course offers hands-on experience of processing sequencing data to construct genomes, identifying genomic variants and applying downstream methods, such as phylogenetics. Further, the course covers transcriptomic and proteomic analysis in human and pathogen settings. High profile examples, including malaria, TB and MRSA, will be used to illustrate the concepts, and there is a strong emphasis on how to implement the methods in practice, with the majority of sessions computer-based.

    Prerequisites

    This course focuses on bioinformatic, population genetic, statistical and genetic epidemiological methods for analysing large genetic datasets.  Participants would be expected have some familiarity with molecular biology, and relevant statistical concepts such as a linear regression.

    Course fee

    The fee for 2022 is £550.

    Course objectives
    Course objectives - Infectious Disease 'Omics
    Paragraph

    Objectives

    By the end of the course participants will be able to:

    • Process raw sequence into a set of informative variants, through mapping to a reference genome or using de novo or reference-free assembly approaches;
    • Conduct transcriptomic and proteomic analysis, in an integrated systems biology approach
    • Perform downstream population genetic and association analysis

    Teaching Programme

    The programme will include the following concepts:

    • Genomic variation and technologies, data visualisation and quality control
    • Mapping to a reference pathogen genome and variant detection
    • Transcriptomics and RNA-seq
    • Assembly of pathogen genomes
    • Phylogenetic analysis and detection of genic selection
    • Exploring Host-pathogen interactions

    Assessment

    There is no formal assessment but a Certificate of Attendance will be provided.

    Requirements

    English Program Requirements

    English Language requirements

    As part of the application process, applicants are required to demonstrate how they meet LSHTM's minimum English Language requirements. This is particularly important for applicants requiring a Student Visa, as the UK Home Office requires that every student from outside the UK and Republic of Ireland shows evidence of a minimum level of English language ability (called CEFR B2 level) in order to be granted a Student visa and study in the UK.

    Additionally, LSHTM asks for English language proficiency levels that are necessary for our academic programmes, which is slightly higher than the Common European Framework for languages (CEFR) B2 level.

    English language requirements policy (pdf)

    Accepted English language tests

    The academic English language requirements for each of LSHTM’s programmes are categorised into one of three profiles:

    • Band A (highest requirement)
    • Band B (mid-range/’standard’ requirement)
    • Band C (lowest requirement)

    Please refer to the appropriate Programme Specification for the English language requirement Band of your preferred programme.

    • IELTS (Academic)
    • Pearson PTE Academic

    These tests are only valid for entry for 2 years. As a result the qualification must have been completed no more than 2 years prior to enrolment.

    LSHTM requires the following minimum proficiency test scores. Please refer to the appropriate Programme Specification for the Band of your preferred programme.

      Band A Band B Band C
    IELTS (Academic)

    7.5 overall with 7.0 in each component

    7.0 overall with 6.5 in each component

    6.5 overall with 6.0 in each component

    Pearson PTE Academic

    80 overall with 80 in each component

    76 overall with 76 in each component

    59 overall with 59 in each component

    Majority English-speaking countries

    Last updated: 26 October 2022

    The UK Government recognises the following countries as majority English-speaking countries:

    • Antigua and Barbuda
    • Australia
    • The Bahamas
    • Barbados
    • Belize
    • Dominica
    • Grenada
    • Guyana
    • Ireland
    • Jamaica
    • Malta
    • New Zealand
    • St Kitts and Nevis
    • St Lucia
    • St Vincent and the Grenadines
    • Trinidad and Tobago
    • United Kingdom
    • United States of America

    These countries have been classified as majority English-speaking countries by the UK Government. Further information on Student Visa requirements, including Knowledge of English, can be found on the government website. In the interest of compliance, LSHTM is not able to consider other countries as majority English-speaking countries.

    If you are a national of one of these countries, you are not required to submit evidence of English language proficiency.

    If you have undertaken a full degree in one of the above countries, you will not be required to submit further evidence of your English Language if the degree certificate is successfully verified with the issuing body on receipt. Any applicant found to have submitted fraudulent documentation will have their application withdrawn.

    Canadian nationals are also exempt from English Language requirements but non-Canadian nationals who have studied in Canada are required to meet standard English Language requirements due to Home Office policy.

    Conditions

    If you request to defer your entry to LSHTM, we may ask you to re-take your test if your original offer was based on a test which will be out of date at the point of registration. Our English language programme requirements and other accepted tests provide details of how long your qualification is deemed valid.

    All test scores are verified with the issuing body on receipt. Any applicant found to have submitted a fraudulent score will have their application withdrawn.

    LSHTM reserves the right to change minimum English Language requirements during an application cycle in-line with any compliance guidance released by the Home Office. In the event of a change in Home Office policy which affects entry requirements, the University will notify affected applicants in writing.

    Exemptions

    Applicants who are a national of a majority English-speaking country or who have successfully completed an appropriate academic qualification (at least equivalent to a UK Bachelor's degree), which was taught in a majority English speaking country from the UKVI approved country list automatically meet our English Language requirements.

    • UKVI’s approved country list

    *Please note, Canadian nationals are exempt from English Language requirements but non-Canadian nationals who have studied in Canada are required to meet LSHTM’s standard English Language requirements due to Home Office regulations.


    Academic entry requirements

    LSHTM's minimum entry requirements for each of its degrees are listed below. Applicants who do not meet the minimum entry requirement for the programme of their choice but who have relevant professional experience may still be eligible for admission.

    Master's programmes (intensive)

    In order to be admitted to an LSHTM master's degree programme, an applicant must:

    • hold either a first degree at Second Class Honours (2:2) standard in a relevant discipline, or a degree in medicine recognised by the UK General Medical Council (GMC) for the purposes of practising medicine in the UK, or another degree of equivalent standard awarded by an overseas institution recognised by UK ENIC or the GMC).

    or

    • hold a professional qualification appropriate to the programme of study to be followed obtained by written examinations and judged by LSHTM to be equivalent to a Second Class Honours (2:2) degree or above.

    or

    • have relevant professional experience or training which is judged by LSHTM to be equivalent to a Second Class Honours (2:2) degree or above.

    and

    • satisfy any additional requirements where prescribed for admission to a specific programme.

    If you have not previously studied in the UK, you can check our guide to international equivalent qualifications for our master's degrees.

    Some degree programmes may have a higher entry requirement than specified above. Please be sure to check the individual programme for any additional entry requirements.

    MPhil and PhD

    Academic requirements

    The normal minimum entrance qualification for registration at the School on a MPhil/PhD programme is evidence of an aptitude for research and at least one of the following:

    • a master’s degree in a subject appropriate to the course of study to be followed (recommended)
    • a qualification appropriate to the course of study to be followed, in medicine, dentistry or veterinary studies
    • an Upper Second Class Honours (2:1) degree from a UK university, or an overseas qualification of an equivalent standard, in a relevant subject.

    English language requirements

    If English is not your first language, you will need to meet these requirements: Band B.

    DrPH

    Academic requirements

    The normal minimum entrance qualification for registration at the School on a Doctoral programme is evidence of an aptitude for research and at least one of the following:

    • a master’s degree in a subject appropriate to the course of study to be followed (recommended)
    • a qualification appropriate to the course of study to be followed, in medicine, dentistry or veterinary studies
    • an Upper Second Class Honours (2:1) degree from a UK university, or an overseas qualification of an equivalent standard, in a relevant subject.

    Applicants for the DrPH study are also required to have a minimum of two year's appropriate experience.

    English language requirements

    If English is not your first language, you will need to meet these requirements: Band B.


    Essential digital skills

    Digital skills and using computers are an everyday part of modern life – and you'll need both during your time at LSHTM.

    You'll need to be able to use standard software (such as Word), a web browser and email. You'll also need to be able to type at a reasonable speed in order to perform to the best of your ability during any online assessments – for reference, the average person types around 40 words per minute – there are a number of free typing speed tests available online.

    It'll benefit your studies if you know how to:

    • use digital technologies to find, evaluate and create information
    • communicate effectively with online technologies
    • select the correct tools to complete online and offline tasks
    • perform tasks efficiently in a variety of digital environments

    Whatever you're studying you'll need to know how to work with digital technologies, stay safe online and build a positive online presence.

    Reasonable adjustments and support are available for students who have additional accessibility or learning needs, and LSHTM recognises the use of voice to text or alternative software being available for those students with disabilities.

    Career

    Objectives

    By the end of the course participants will be able to:

    • Process raw sequence into a set of informative variants, through mapping to a reference genome or using de novo or reference-free assembly approaches;
    • Conduct transcriptomic and proteomic analysis, in an integrated systems biology approach
    • Perform downstream population genetic and association analysis

    Teaching Programme

    The programme will include the following concepts:

    • Genomic variation and technologies, data visualisation and quality control
    • Mapping to a reference pathogen genome and variant detection
    • Transcriptomics and RNA-seq
    • Assembly of pathogen genomes
    • Phylogenetic analysis and detection of genic selection
    • Exploring Host-pathogen interactions

    Assessment

    There is no formal assessment but a Certificate of Attendance will be provided.

    Fee Information

    Tuition Fee

    GBP 0 

    How to Apply

    Applying for CPD and short courses

    All of our short courses can be applied for online. Details on how to apply including fees and payment deadline can be found the page of the course you are interested in. A link to the online application form will be found on the tab of the chosen course. For a full details of what is on offer, please visit our short courses section.

    Please also read our Continuing Professional Development (CPD) and short courses admissions policy before applying for a course.

    Applying for London-based modules

    Details on how to apply including fees and payment deadline can be found on the London-based module section of the website. Applicants for individual modules should complete the MSc module application form and email it to shortcourses@lshtm.ac.uk.

    Please note that the School gives priority to the needs of students registering for masters and research degrees, and so places on any module may be limited.

    Applying for distance learning modules

    Applications should be made online to the University of London international programmes. Applicants should go to the relevant programme webpage and click on the corresponding ‘Apply online’ tab. Please see below for the list of available modules per programme and to apply:

    • Clinical Trials modules
    • Demography & Health modules
    • Epidemiology modules
    • Global Health Policy modules
    • Infectious Diseases modules
    • Public Health modules

    Further information on the application process for the distance learning programmes can be found on the University of London website.

    London School of Hygiene & Tropical Medicine, University of London

    Infectious Disease 'Omics

    London School of Hygiene & Tropical Medicine, University of London

    [object Object]

    United Kingdom,

    Camden

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